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| Husband: Francis Smith Preston
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| Born: | 2 Aug 1765 | at: | Smithfield Plantation, Blacksburg, Augusta (now Montgomery) Co. VA
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| Married: | 10 Jan 1793 | at: |
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| Died: | 26 May 1835 | at: | Columbia, Lexinbgton / Richland Co. SC |
| Father: | Col. William C. Preston
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| Mother: | Susanna Smith
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| Spouses: | Sarah Buchannan Campbell
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| Wife: Sarah Buchannan Campbell
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| Born: | 21 Apr 1778 | at: | Beverley Manor, Augusta Co. VA
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| Died: | 23 Jul 1846 | at: |
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| Father: | Gen. William C. Campbell
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| Mother: | Elizabeth Henry
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| Spouses: | Francis Smith Preston
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| CHILDREN
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| Name: |
Gen. John S. Preston
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| Born: | AFT. 1793 | at: |
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| Died: | | at: |
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| Spouses: | |
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| Name: |
Gov. William Campbell Preston
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| Born: | 27 Dec 1794 | at: | Philadelphia, Philadelphia Co. PA
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| Married: | | at: |
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| Died: | 22 May 1860 | at: | Columbia, Lexinbgton / Richland Co. SC |
| Spouses: | Mary [1] Coalter
, Louisa Penelope Davis
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| Name: |
Eliza Henry Preston
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| Born: | 11 Aug 1796 | at: | Saltville, Smyth Co. VA
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| Married: | | at: |
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| Died: | 11 Jan 1877 | at: | Charlottesville, Albemarle Co. VA |
| Spouses: | Edward Codrington Carrington
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| Name: |
Francis Smith Preston
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| Born: | ABT. 1798 | at: |
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| Died: | | at: | young |
| Spouses: | |
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| Name: |
Susanna Smith Preston
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| Born: | 5 Mar 1800 | at: | Saltville, Smyth Co. VA
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| Married: | Sep 1818 | at: |
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| Died: | 13 Oct 1847 | at: |
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| Spouses: | Gov. James McDowell
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| Name: |
Sarah Buchanan Preston
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| Born: | 14 Feb 1802 | at: | Saltville, Smyth Co. VA
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| Married: | | at: |
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| Died: | 1879 | at: | Abingdon, Washington Co. VA |
| Spouses: | Gov. John Buchanan Floyd
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| Name: |
Anne Sophonisba Preston
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| Born: | 9 Apr 1803 | at: | Abingdon, Salt Works, Washington Co. VA
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| Married: | 11 Mar 1823 | at: | Abingdon, Washington Co. VA
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| Died: | 21 Dec 1844 | at: | Baltimore, Baltimore Co. MD |
| Spouses: | Rev. Dr. Robert Jefferson Breckenridge
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| Name: |
Jane Robertson Preston
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| Born: | 13 Jun 1804 | at: |
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| Died: | Aug 1804 | at: |
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| Spouses: | |
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| Name: |
Maria Thornton Carter Preston
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| Born: | 26 Aug 1806 | at: | Saltville, Smyth Co. VA
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| Married: | 20 Sep 1832 | at: |
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| Died: | 18 Oct 1842 | at: | Abingdon, Washington Co. VA |
| Spouses: | John Montgomery Preston
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